All Panel NGS Cancer Screening Test

COMPONENTS – BCR-ABL/ t (9;22) (q34; q11.2), TEL-AML1, ETV6-RUNX1/ t (11;21) (p13; q22), E2A BA, TCF3 BA/ t (1;19)/t (17;19), MLL BA/ t (4;11) (q21; q23)/ t (9;11) (p22; q23)

CLINICAL UTILITY – the ALL FISH profile detects cytogenetic abnormalities commonly associated with acute lymphoblastic leukemia (ALL). Identification of specific abnormalities defines various subtypes of ALL that have different prognosis and responsiveness to specific therapies

METHODOLOGY – fluorescence in situ hybridization (FISH) or next generation sequencing (NGS)

TURN AROUND TIME – 7 days

PATEINT PREPARATION –

COLLECT – not-diluted bone marrow aspirate or whole blood in sodium heparin

SPECIMEN PREPARATION – transfer 3-4ml bone marrow or peripheral blood in heparin vacutainers

STORAGE/TRANSPORT TEMPERATURE – 2-8 degrees C (with cold pack)

STABILITY – ambient: 48 hours, refrigerated: 48 hours

UNACCEPTABLE CONDITIONS – clotted specimens

MRP – 13500

SPECIAL INSTRUCTIONS – clinical history is mandatory including histopathology reports