C-MYC Gene Rearrangement

DESCRIPTION – this rearrangement occurs in DLBCL (diffuse large B-cell lymphomas. It has poor prognosis. This test is used to order individual or multiple oncology FISH probes

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 12 days

PATIENT PREPARATION –

COLLECT – tumor tissue

SPECIMEN PREPARATION – formalin fixed paraffin embedded tissue block. Protect the slides from excessive heat

STORAGE/TRANSPORT TEMPERATURE – room temperature (8-25 degrees C)

UNACCEPTABLE CONDITIONS – alternate fixatives and decalcified specimens

STABILITY – ambient: indefinitely; refrigerated: indefinitely

MRP – 8000

SPECIAL INSTRUCTIONS – clinical history is mandatory, please bring your previous health reports with you