Estrogen

Description- Estrogen receptor-alpha is a prognostic tool for breast cancer. This test is predictive for response of breast cancers to hormonal therapy and also differentiates endocervical from endometrial adenocarcinomas

Mnemonic - ER IHC

Approach- Immunohistochemistry

Specimen needed Patient Preparation
Assortment of sample from - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature for the specimen - At temperature or cold. Transport it in cooled instrumentation throughout weather.
Specimen rejection- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable