P501S

Prostein

Description: Prostein (Prostate cancer-associated protein 6) is a prostate-specific, 553 amino acid type IIIa plasma transmembrane protein that is upregulated by androgens. It has a perinuclear-like staining pattern, as expression is found in the Golgi complex of prostate cells. Prostein was positive in 99% of metastatic prostate adenocarcinomas while 97% of cases were positive for PSA. Prostein in conjunction with PSA improves identification of prostatic origin in unknown primary lesions, when staining alone with Prostein or PSA. Prostein is useful in diagnosing and monitoring prostate cancer.

Methodology: Immunohistochemistry

TAT: 3-5 days

Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable