PAX8
Description- PAX8 is expressed in high percentage of ovarian serous, endometroid, and clear cell carcinomas, but expressed rarely in primary ovarian mucinous adenocarcinomas. It is an important marker of ovarian cancer and useful marker for the differential diagnosis in lung and neck tumors, or tumors at distant sites where primary lung carcinoma, breast carcinoma, or thyroid carcinoma are possibilities.
Methodology: Immunohistochemistry
TAT: 3-5 days
Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable

