Smooth muscle actin
Description- SMA stands for smooth muscle actin. It reacts with the alpha-smooth muscle isoform that is present in smooth muscle cells of vessels, parenchymes, myoepithelial cells, pericytes, and some stromal cells in the intestine, testis, and ovary. This test aids in differentiating leiomyosarcoma from rhabdomyosarcoma
Methodology: Immunohistochemistry
TAT: 3-5 days
Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable