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BRCA 1 & BRCA 2 Profile Complete Gene Sequencing

BRCA 1 & BRCA 2 Profile Complete Gene Sequencing

What is the purpose of a BRCA 1 & 2 Profile Complete Gene Sequencing Test?

The BRCA1 and BRCA2 genes are well-known for their involvement in hereditary breast and ovarian cancer syndrome (HBOC), which is caused by mutations in either of these genes. Additionally, these genes have been associated with an increased risk of other types of cancer, such as prostate and pancreatic cancer.

A BRCA1 & 2 Profile Complete Gene Sequencing Test is a type of genetic testing that is used to identify mutations in these genes. The purpose of this test is to determine if a person has a genetic predisposition to developing certain types of cancer, particularly breast and ovarian cancer.

The sequencing of these genes involves a process that allows for the identification of specific mutations in the DNA sequence of the BRCA1 and BRCA2 genes. This test can detect both inherited and de novo (new) mutations in these genes. It is important to note that not all mutations in these genes are known to increase cancer risk, and some mutations may be classified as variants of unknown significance (VUS), meaning their clinical significance is unclear.

The BRCA1 & 2 Profile Complete Gene Sequencing Test typically involves the use of next-generation sequencing (NGS) technology, which allows for a more comprehensive analysis of the entire gene sequence. This can provide more accurate results and may detect rare or previously unknown mutations that could be clinically relevant.

How accurate is a BRCA 1 & 2 Profile Complete Gene Sequencing Test?

The BRCA1 and BRCA2 genes are known to be linked to hereditary breast and ovarian cancer. Mutations in these genes can also increase the risk of developing other types of cancer such as prostate and pancreatic cancer.

To accurately detect mutations in these genes, a BRCA1 & 2 profile complete gene sequencing test is recommended. This test uses next-generation sequencing (NGS) technology to sequence the entire coding regions and splice junctions of both genes.

The accuracy of this test is quite high, with a reported sensitivity and specificity of up to 99.9%. However, it is important to note that no genetic test is 100% accurate. There is always a possibility of false negatives or false positives.

It is also important to consider that this test only detects mutations in the BRCA1 and BRCA2 genes. There are other genes that have been linked to hereditary cancer that are not

included in this panel. Therefore, depending on the individual's family history and personal risk factors, additional genetic testing may be necessary.

In summary, the BRCA1 & 2 profile complete gene sequencing test is a highly accurate method for detecting mutations in these genes. However, it is important to consider the limitations of this test and to consult with a healthcare provider or genetic counselor to determine the most appropriate testing strategy based on individual risk factors.

What type of information does a BRCA 1 & 2 Profile Complete Gene Sequencing Test provide?

The BRCA 1 & 2 Profile Complete Gene Sequencing Test is a genetic panel that analyzes the entire sequence of the BRCA1 and BRCA2 genes in order to detect mutations that may increase the risk of developing hereditary breast, ovarian, prostate, and pancreatic cancer.

This test provides comprehensive information on the genetic makeup of these two crucial genes, which are responsible for repairing damaged DNA and preventing the formation of cancer cells. Mutations in these genes can interfere with their function and increase the likelihood of developing cancer.

The complete gene sequencing test involves the use of next generation sequencing (NGS) technology to accurately sequence the entire BRCA1 and BRCA2 genes. This allows for detection of all known mutations, including point mutations, small insertions and deletions, and copy number variations.

The results of this test can provide individuals and their healthcare providers with valuable information about their risk for developing certain types of cancer. A positive result indicates the presence of a harmful mutation in one of these genes, which means that the patient has an increased risk of developing cancer and may require more frequent cancer screenings or risk-reducing surgeries. On the other hand, a negative result indicates that no harmful mutations were found, which can provide reassurance to patients and inform their future medical decisions.

What should I expect during and after a BRCA 1 & 2 Profile Complete Gene Sequencing Test?

The BRCA1 and BRCA2 genes are responsible for producing proteins that help to suppress tumor growth. Mutations in these genes can increase the risk of developing breast, ovarian, prostate, and pancreatic cancer. If you have a family history of these types of cancers, you may want to consider getting a BRCA1 & 2 Profile Complete Gene Sequencing Test.

During the test, a sample of your DNA will be taken, usually through a blood or saliva sample. The DNA sequence of your BRCA1 and BRCA2 genes will then be analyzed using next-generation sequencing technology. This will allow for a comprehensive assessment of any mutations or variations in these genes.

After the test, the results will be interpreted by a molecular geneticist or a genetic counselor. They will provide you with a detailed report of any mutations or variations found in your

BRCA1 and BRCA2 genes. They will also discuss your risk of developing cancer based on these results and recommend any further testing or screenings that may be necessary.

If a mutation is found in your BRCA1 or BRCA2 genes, it does not mean that you will definitely develop cancer. However, it does mean that your risk of developing cancer is higher than the general population. Your doctor may recommend increased surveillance, prophylactic surgery, or other risk-reducing measures.

What is the cost of a BRCA 1 & BRCA 2 profile complete gene sequencing test in Delhi?

BRCA 1 & BRCA 2 profile complete gene sequencing test is an important diagnostic tool in the field of pathology which helps in identifying pathogenic mutations that increase the risk of developing breast and ovarian cancer. The cost of this test may vary depending on various factors such as the location of the diagnostic center, the type of laboratory or pathology clinic, and the level of expertise of the medical professionals involved.

In Delhi, the cost of a BRCA 1 & BRCA 2 profile complete gene sequencing test may range from INR 20,000 to INR 40,000. However, it is important to note that the cost may also vary based on the type of diagnostic center you select. For instance, a diagnostic center with advanced technologies and equipment may charge more for the test compared to a smaller, less advanced center.

It is recommended to choose a reputable pathology clinic or pathlab that has a team of experienced medical professionals who specialize in genetics and molecular biology. The team should be able to provide accurate and reliable test results along with appropriate counseling and support to patients.

CNC Pathlab is a renowned pathology clinic in Delhi that provides a wide range of diagnostic tests including BRCA 1 & BRCA 2 profile complete gene sequencing test. They have a team of expert medical professionals who are trained in genetics and molecular biology and use advanced technology to provide accurate and reliable test results. Furthermore, they also provide appropriate counseling and support to patients.

How long does it take to get results from a BRCA 1 & BRCA 2 profile complete gene sequencing test in Delhi?

The time taken to get results from a BRCA 1 & BRCA 2 profile complete gene sequencing test in Delhi can vary depending on various factors such as the testing laboratory, the type of sequencing method used, and the volume of tests being processed. However, on average, it can take anywhere between 10-14 working days to receive the test results.

It is important to note that BRCA 1 & BRCA 2 profile complete gene sequencing test should only be performed under the guidance of a qualified genetic counselor or physician. This is because the results of the test can have significant implications for an individual's health and can be used to make important decisions regarding their medical management.

At CNC PathLab, we offer comprehensive and reliable diagnostic and testing services, including BRCA 1 & BRCA 2 profile complete gene sequencing test, to patients across India. Our state-of-the-art facilities and advanced testing methods ensure accurate and timely results, while our team of experienced pathologists and genetic counselors provide personalized guidance and support to our patients throughout the testing process.

The timely diagnosis and screening may help you easily to avoid diseases and with CNC Pathlab BRCA 1 & BRCA 2 Profile Complete Gene Sequencing you can easily track your health records in the best way. CNC Pathlab is the most trusted and leading diagnostic lab for providing all kinds of health services to customers. You can opt for the BRCA 1 & BRCA 2 Profile Complete Gene Sequencing test, or other tests that are better suited to your needs in order to maintain your health from your comfort place (at home services).

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